Drucker commented: GLP1 [drugs] have given us so many wonderful results, but tackling these very challenging brain disorders has been disappointing There was a hope that we would see some benefit, and we didnt. From the Alzheimers Drug Discovery Foundation (ADDF), Howard Fillit, MD, emphasized that even negative trials move the field forward, pointing to the need to target the broader pathobiology of Alzheimers and to consider preventive or combination approaches informed by biomarker profiles
Combination with muscle-preserving agents: Companies developing myostatin and activin pathway inhibitors alongside GLP-1RAs are addressing a real unmet need that Novo Nordisk and Eli Lilly are also pursuing but have not yet solved
Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, United States, 79905 Email: [email protected]
Rare, More Serious Side Effects Anecdotal Side Effects There has also been plenty of media buzz about anecdotal side effects with names like Ozempic face and Ozempic butt. These cosmetic side effects arent unhealthy, and arent directly caused by GLP-1s