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Their activation initiates inflammatory and fibrogenic cascades that drive the progression from simple steatosis to non-alcoholic steatohepatitis (NASH) and hepatic fibrosis
Thyroid follicular cells in HT patients can aberrantly express both B7.1 and MHC class II molecules, enabling them to function as non-professional APCs and directly participate in autoimmune activation
Chamberlain, G., Fox, J., Ashton, B
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