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[5] Use of Lipo-C Injection is contraindicated in patients with known hypersensitivity to methionine, choline salts, carnitine, dexpanthenol, or any formulation excipients, as well as in individuals with severe hepatic failure in whom augmented methionine intake could precipitate hypermethioninemia and encephalopathy

J Cataract Refract Surg 23:15721576 Hsu TH, Chu CC, Hung MW, Lee HJ, Hsu HJ, Chang TC (2013) Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell-cycle arrest in human cervical cancer cells

The same research group also published a study in older adults with HIV showing similar benefits, including reduced oxidative stress and improved mitochondrial fatty acid oxidation (Kumar et al., Antioxidants, 2020) [30]