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Vlado Perkovic Tweets That They Are Stopping FLOW Early for Efficacy We will have to wait for the presentation and publication of the manuscript to fully understand the details and cost-benefit implications of semaglutide in chronic kidney disease (CKD), but this result was not unexpected
While semaglutide targets only GLP-1 receptors, tirzepatide is a dual agonist that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, adding a second metabolic pathway to the mechanism
It is not a medical treatment or cure
For Wegovy, the target maintenance dose is 2.4 mg administered as a weekly injection
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