The Phase II Trial (NCT01349959) of azacitidine combined with entinostat in TNBC showed limited clinical efficacy, despite considering epigenetic changes (e.g., reduced methylation), indicating that better results could be achieved with higher dosages or combinatorial immunotherapy [241]
PHARMA Eli Lilly Pays $2.8B for a Psychedelic-Medicine Bet Forbes reports Eli Lilly is acquiring AtaiBeckley, the psychedelic-medicine biotech Christian Angermayer built after a personal mushroom trip convinced him FDA-approved drugs could come from psychedelics, in a $2.8 billion deal
Additional Functional Tests Glucose & insulin levels (to check for insulin resistance, PCOS) CRP or hs-CRP (systemic inflammation) Vitamin D (supports hormone and immune function) Stool test (for gut inflammation, microbiome health, and estrogen clearance) Best Time to Test (For Cycling Women) If you are a woman, when you collect your sample mattersespecially if you're trying to understand cyclical hormone shifts
The same paper reported improved physical performance after outside MOTS-C treatment in mice, not people