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A1c, glucose and weight are still trending down, vast improvements in cardiometabolic markers
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Combination Compounds (CagriSema and others) The CagriSema program (cagrilintide combined with semaglutide) represents the combination-formulation approach to broadening mechanism: pairing two compounds with complementary mechanisms rather than building one larger molecule [4]
As a GLP-1 receptor agonist, it stimulates insulin secretion in a glucose dependent manner, inhibits glucagon secretion, slows down gastric emptying, and promotes satiety
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