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The SURMOUNT-5 trial found approximately 20.2% average body-weight loss with branded tirzepatide versus 13.7% with branded semaglutide over 72 weeks in adults with obesity and without diabetes
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These medicines are typically administered by subcutaneous injection, though oral formulations of semaglutide are also available
Semaglutide and phentermine have both been shown to be effective at helping people to lose weight
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