25 semaglutide Internet searches on weight-loss medications have increased 25-fold since the launch of GLP-1 drugs and a shorter life SEMAGLUTIDE

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Ueda P, Svanstrm H, Sderling J, Pazzagli L, Wintzell V, Eliasson B, Hviid A, Pasternak B

Although there was a slight increase in oral semaglutide exposure when taken in combination with omeprazole (possibly due to the increase in gastric pH), the increase observed was not statistically significant and was considered by the investigators to likely not be clinically relevant

So, for those reasons, medications can sometimes be very helpful, but I try not to push people into taking pills