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Neurogenesis and CNS Ageing: Combinable Mechanisms In the hippocampal SGZ, both TERT-dependent neurogenic capacity (Epitalon) and oxidative stress-dependent neuronal survival (GHK-Cu) contribute to the age-related decline in adult neurogenesis

Can Res 55:47714775 Mulcahy RT, Gipp JJ (1995) Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene

NADPH is used as a cofactor by glutathione reductase (GR) to reduce oxidized glutathione (GSSG2GSH), and likewise by thioredoxin reductase to reduce oxidized thioredoxin

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