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This is conferred by a targeted amino acid substitution at the 8th position, replacing alanine with glutamic acid, a modification also found in exenatide-based GLP-1 therapies
They will also explore targeted uses, including therapies involving transplanted pancreatic cells
Int Immunopharmacol 81:106267
These medicines include tricyclic anti-depressants (amitriptyline), serotonin-noradrenaline reuptake inhibitors (duloxetine and venlafaxine), and selective serotonin reuptake inhibitors (fluoxetine and paroxetine)
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