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Worsley, C
3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance
In the current study, the investigators administered the IGFBP2-derived peptide, called JB2, to mice with SHANK3 mutations
Set expectations accordingly: BPC-157 is a promising tool for knee rehabilitation, not a proven therapy
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