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Otolaryngology-Head and Neck Surgery 137 (3), S1S31 (2007)
Then, the pyrimidine ring and 5-pyriphosphoribosyl pyrophosphate (5-PRPP), generated from the pentose phosphate pathway (PPP), are catalyzed to form orotidine 5-monophosphate (OMP) via dihydroorotate dehydrogenase (DHODH)
The trial lasted for 68 weeks
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