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Moreover, transcriptomic analysis from the LOVIT trial revealed that vitamin C lowered mortality in adaptive but worsened outcomes in inflammopathic sepsis, suggesting immune profiling may guide personalized therapy (Rynne et al., 2025)

NCT05394519 ClinicalTrials.gov

When speaking to your GP, it may be helpful to: Be honest about your weight history and any previous attempts at lifestyle modification or pharmacological treatment