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The chemical was given using the forced-feeding method directly to the stomach of the rat
It is approved by the Food and Drug Administration (FDA) for the treatment of type 2 diabetes, but it has also been prescribed off-label for weight loss purposes
If he had his way, Cuban said that every healthcare provider, pharmacy middleman, and "any affiliated in any way company" would be required to "publish their un-redacted contracts, for all to see." "Prices could drop 30% across all of healthcare in a year," he said
Metformin is sometimes used off-label in this age group for insulin resistance, though its weight-loss effect is modest (1 to 2 kg over 6 months based on a Cochrane review of pediatric metformin studies) [11]
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