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83 amino acids Modifications: Arg substitution (GluArg at IGF-1 position 3) for reduced IGFBP-3 affinity

However, dexamethasone mitigates ovalbumen-induced eosinophilic airway inflammation, including airway hyperresponsiveness, leukocyte infiltration, goblet cell hyperplasia, Th2 cytokine production, and the expression of pyroptosis markers, by inhibiting the HIF-1-glycolysis-lactate axis and subsequent protein lactylation