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The studies varied in design, patient population, and outcome measures, making direct comparisons challenging
This rare condition can lead to: low plasma carnitine progressive cardiomyopathy, or heart muscle disease skeletal myopathy hypoglycemia hypoammonemia weak muscles in the hips, shoulders upper arms, legs, neck, and jaw muscles Untreated it is fatal
In clinical trial protocols, the drug is initiated at a low dose and titrated gradually upwards to minimise gastrointestinal side effects
This was not the case for other intestinal hormones such as GIP
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