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When the digestive tract slows down drastically, it can lead to a backlog in the system, resulting in a variety of uncomfortable symptoms
Describing herself as largely 'the lab rat' when she joined the diabetes team, Knudsen remembers she spent 'the first year in a cold room with three technicians to screen hundreds of thousands of compounds to see if they could wedge into the GLP-1 receptor and other targets of interest just snugly enough to stimulate insulin secretion.' To help speed up the screening process, Knudsen devised a method to test 96 candidates in one go instead of just one
Patients who combine GLP-1 therapy with dietary changes and increased physical activity typically experience faster and more significant weight loss than those relying on medication alone
Figlioli G., et al
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