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These factors can change the needed dosage
Initial research tested doses as low as 250mcg and as high as 1mg daily
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Some miRNAs (miR-21, miR-29b, miR-144-3p, miR-148a, miR-210, miR-205-5p) enhance adipogenesis by interfering with the expression of anti-adipogenic signaling pathways (TGF-, TNF-, Wnt, co-repressors of C/EBP)
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