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PT141 may stimulate the melanocortin system and alter sexual desire or vascular tone
Retatrutide, a triple agonist in Phase 3 clinical trials, produced average weight loss of 24 percent at 48 weeks in Phase 2 data (Jastreboff et al., NEJM , 2023)
Metabolic health, cardiovascular resilience, cognitive function, and long-term protection against neurodegeneration are all plausibly within reach of a therapeutic strategy that addresses both the hormonal and metabolic dimensions of the menopausal transition simultaneously
Bruemmer says its an essential component of any ultimately successful treatment
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