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(The drinks popularity has since declined.) Podcaster Alex Cooper hit the market with her own beverage brand, Unwell Hydration, in 2024, which gained Target distribution in 2025, and expanded into the energy drink branch with Unwell Energy in December

and significantly increased levels of the endogenous antioxidant superoxide dismutase

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Given that DPP-4 clearly plays a role in the clearance of a number of hormones involved in the regulation of glucose homeostasis, the question arises of whether changes in DPP-4 activity might play a role in the pathogenesis of T2DM