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Next-gen incretin competitors, even when not strict GLP-1 RAs, pressure incumbent GLP-1 franchises and can change the value of late-cycle life-cycle extensions
Many biologic and peptide-based medicines including insulin and injectable semaglutide share this limitation
Typically, more significant weight reductions become evident within a few months as patients reach their optimal dose
Lowers rates of non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death
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