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I mentioned previously that the symptoms of B12 deficiency can mimic hypothyroid symptoms which can make the diagnosis hard to spot

Incretin-based therapies work either by preventing enzymatic degradation of GLP-1, thus maintaining plasma levels of endogenous GLP-1 (dipeptidyl peptidase 4 inhibitors, DPP4is) or by directly activating GLP-1 receptors and mimicking the action of native GLP-1 (glucagon-like peptide-1 receptor agonists, GLP-1 RAs) [9]

Trial data consistently show that patients who rush escalation have more nausea and vomiting, while those who stay on each step for the full month tolerate the drug better

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