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GLP-1 receptor agonists have been shown to reduce systemic inflammation through several mechanisms: Reducing oxidative stress: GLP-1s can reduce oxidative stress, a key contributor to inflammation

However, CU is considered a poor candidate drug due to its low bioavailability, rapid clearance, and metabolism

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Interventions: VK2735 Primary Outcome Measure: Percent change in body weight from baseline to Week 78 in body weight Time Frame: 78 weeks Study Details Source A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight Sponsor: Novo Nordisk A/S Goal: This study will look at how well CagriSema helps people with excess body weight lose weight