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(2012)s investigation, FX exhibited antidiabetic activity through inhibiting human recombinant aldose reductase (HRAR), rat lens aldose reductase (RLAR), protein tyrosine phosphate 1 (PTP 1), and advanced glycation end-product (AGE) formation
& Kishi, K
Metformin Reverses Hashimotos Thyroiditis by Regulating Key Immune Events
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This process also contributes to the removal of damaged organelles, such as mitochondria and ER, and misfolded or aggregate-prone proteins (Mizushima, 2011)
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