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doi:10.1093/jn/130.4.1007s

If GHK-Cu penetrates poorly through intact skin, the observed clinical effects could be occurring primarily at the epidermal level rather than reaching dermal fibroblasts where collagen synthesis occurs

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longer under freezer storage when documentation supports it Lyophilized powder for long-term storage -20 C freezer, dry container, minimal temperature cycling Best option for long-term retention before reconstitution Reconstituted BPC-157 2-8 C refrigerator, protected from light About 28 days as a conservative default unless supplier data says otherwise Unknown temperature history Not reliable Discard or replace rather than guessing Lyophilized BPC-157 Lasts Longer Than Reconstituted BPC-157 Most research BPC-157 is supplied as lyophilized powder