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For glycemic control, the mean reduction in HbA1c across most T2DM subgroups approaches or reaches the commonly referenced threshold for clinical relevance of 0.5% 47 , and in key target populations (e.g., T2DM with obesity) can reach 0.81.0%, indicating clinically perceptible improvements
The severity of these reactions can range from mild, temporary discomfort to more severe, persistent symptoms
Nauck et al., 2009
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