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This is the most legitimate path to access but requires finding a willing prescriber
From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles
These changes are continuing to have serious effects on the distribution and abundance of natural populations and species, and they possess a serious threat to biodiversity (91)
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