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Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)
Berry, R
They did also talk about One study assessed the mutagenicity and teratogenicity of the compound, basically looking at, do any mutations occur by injecting, or are there any effects of like fetal development? That one study did not prove that there was any kind of that ill effect occurring from BPC-157, but that doesnt mean its safe
Dong Z, Mattocks JA, Deblonde GJ, Hu D, Jiao Y, Cotruvo JA Jr., Park DM (2021) Bridging hydrometallurgy and biochemistry: a protein-based process for recovery and separation of rare earth elements
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