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The relationship between diabetes and cognitive impairment involves many aspects, including central insulin signal transduction, nerve fiber damage caused by hyperglycemia, neuritis, oxidative stress, bloodbrain barrier damage, vascular neuropathy, changes in the dopaminergic system, and the effects of advanced glycation end products on metabolism and energy (Figure 1)
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"Our findings should be viewed as being significant but tentative, as future studies are needed to examine these questions in a much larger and more diverse population," Rizzo said
Prioritizing sleep, healthy eating, and physical activity can help stabilize mood and reduce discomfort
