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Recent clinical and preclinical studies have demonstrated that metformin not only ameliorates insulin sensitivity, but also facilitates glucose-lipid reverse transport, alleviates hormone imbalances induced by glucose metabolic irregularities, and ameliorates symptoms associated with hormonal dysregulation in patients with PCOS (Shen et al., 2022
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It may also help muscle tension and headaches
Panel D of Figure 5 shows that homocysteine undergoes large fluctuations in synchrony with the methionine input as expected
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