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Although this view was later attenuated based on the head-to-head conformation of the DNA-bound DBD dimer that was observed in X-ray crystallography studies and observations of relaxed response element stringency for selective chromatin binding [51, 52], it did point to the potential of variability in the composition of AREs and to deviations from the ideal 15 bp sequence
Like Reply 1 Reaction 2 Reactions Elke Pellicano Phillips 1y Report this comment Like Reply 1 Reaction 2 Reactions Lourdes Castro MS RD 1y Report this comment That is exciting
In addition, although changes in oxidative stress markers have been reported, direct evidence linking GLP-1RA therapy to constrained redox buffering capacity remains limited
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