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Y.ShiM.et al (2006)

376,377 Obesity is a metabolic disorder caused by genetic, environmental, and other factors, which is related to a variety of metabolic diseases, such as diabetes, hypertension, cardiovascular, and cerebrovascular diseases

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The standard retatrutide dose schedule is: Weeks 1-4: 1 mg once weekly Weeks 5-8: 2 mg once weekly Weeks 9-12: 4 mg once weekly Weeks 13-16: 8 mg once weekly Week 17 onward: 8-12 mg once weekly (maintenance) In the combination context, many researchers find that 8 mg is sufficient for their maintenance dose rather than pushing to 12 mg, because the cagrilintide provides enough additional appetite suppression and satiety to make the extra 4 mg of retatrutide unnecessary