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Ensure endotoxin testing below 0.5 EU/mg
doi:10.1016/j.intimp.2023.110138
PEA is thought to work by supporting the inflammatory response through the PPAR-a receptor, COX-2 and through effects on NF-kappaB signaling while also by restoring balance in the endocannabinoid system
If symptoms persist despite these measures, healthcare providers may consider slower dose titration schedules, temporary dose reductions, or prescribing anti-nausea medications for short-term relief
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