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When longer-acting GLP-1 drugs like Ozempic were first approved for human use in the late 2010s, there also was an off-label effect where people were reporting that they were not interested in drinking and that they were not craving alcohol. Studying cravings As craving is one of the core components of addiction, Schacht designed a double-blind trial meaning neither the participants nor the researchers know who is getting semaglutide and who is getting a placebo in which participants take a drug daily for two months and agree to be studied to see how their cravings are affected