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Moreover, DEX treatment (0.5 g/kg/h, pumping injection, before induction of anesthesia to the end of surgery) has been reported to reduce cardiac troponin I and MDA levels and to decrease the incidence of arrhythmias in patients undergoing cardiac valve replacement [234, 235]
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Glutathione-peroxidase1 (Gpx1) is primarily involved in glutathione synthesis in the cochlea, and reduced activity has been linked to NIHL (Ohlemiller et al., 2000
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