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Mass spectrometry detection was performed using a Q Exactive MS (Thermo) in both electrospray ionization positive (ESI+) and negative (ESI-) modes, with optimized settings including a spray voltage of 3.0 kV (ESI+) and 3.2 kV (ESI-), a capillary temperature of 350 C, and a sheath gas flow rate of 45 arb

Compounded medications referenced in this article - including compounded semaglutide and compounded tirzepatide - are not FDA-approved finished drug products and have not been reviewed by the FDA for safety, effectiveness, or quality before marketing

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However, extrapolations can be made by examining guidance in other immune-mediated diseases treated with biologics