Repair of thoracic spinal cord injury by chitosan tube implantation in adult rats
Conflict of interest GW, FK, and TG are employed by Whiteley Corporation

Common side effects of corticosteroids include: Weight gain and increased appetite Fluid retention and bloating Elevated blood glucose levels (or worsening of existing diabetes) Mood changes, including anxiety, irritability, low mood, or in some cases more severe psychiatric reactions such as psychosis Insomnia and sleep disturbance Increased susceptibility to infections Gastrointestinal effects, including indigestion, peptic ulceration, and gastrointestinal bleeding (risk is increased when taken alongside non-steroidal anti-inflammatory drugs) [25] [26] Longer-term or higher-dose use may lead to more serious effects, such as: Osteoporosis and increased fracture risk (bone protection with calcium, vitamin D, and sometimes bisphosphonates may be indicated) Adrenal suppression (where the body's own cortisol production is reduced) Hypertension (high blood pressure) Cataracts and glaucoma Skin thinning and easy bruising Muscle weakness (steroid myopathy) and, rarely, avascular necrosis of bone Impaired wound healing Vaccinations: People taking high-dose systemic corticosteroids should not receive live vaccines (such as MMR or varicella) without specialist advice, as there is a risk of serious infection

Dosage charts for alternative reconstitution volumes Not everyone reconstitutes with 2ml