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PCSK9 inhibitors, such as evolocumab and alirocumab which are developed to treat statin-intolerant high LDL-cholesterol patients, prevent LDLR degradation and increase LDLR recycling back to the cell membrane [129]
Structure of Trypanosoma brucei glutathione synthetase: domain and loop alterations in the catalytic cycle of a highly conserved enzyme
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