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Guan S-S, Sheu M-L, Yang R-S, Chan D-C, Wu C-T, Yang T-H, et al

Al-Nema et al., 2021)

Glutathion Liposomal (L-Glutathion rduit

Hypothesizing that the chloro-methyl-pyrimidine core was responsible for the remaining issues, they explored replacing it with a bicyclic core, leading to Compound 80