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Retatrutide generally improves insulin sensitivity, while high levels of growth hormone can sometimes induce a state of temporary insulin resistance
doi: 10.1038/245323a0 124 DunNJWuSYLinCW
For some people, staying at the same dose for a few weeks before increasing may give the digestive system more time to adapt and reduce the intensity of side effects like constipation, nausea, or bloating, says Hamilton