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Accordingly, unlike exendin-4 and liraglutide, the suppression of food intake caused by peripheral GLP-1 is attenuated by peripheral but not central administration of exendin-9 [21]
Most patients experience weight loss around 1-2.5 pounds per week, ideally around 1% of their own weight
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For weight loss, semaglutide can lead to an average 15% weight loss in a little over a year (an average of 33 pounds in 68 weeks), according to a study in The New England Journal of Medicine
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