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In research models, elevated NNMT activity has been associated with: lower NAD levels, with downstream effects on mitochondrial energy production
An overt B12 deficiency can develop, marked by fatigue or tingling in the hands or feet
Although the number of injections that would be administered would very much depend on the extent of the nerve damage, they are normally administered over several weeks or months
This represents the most common starting point in practical protocols and aligns with the midpoint of clinical dosing ranges adjusted for average body composition
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