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While they are both GLP-1 medications, they have different active ingredients

Treatment with tirzepatide resulted in a mean increase in heart rate of 14, 24 and 36 beats per minute (bpm) for 5-, 10- and 15-mg groups, respectively, at the end of study treatment (Week 40/42 for SURPASS-1, 2 and 5 and Week 52 for SURPASS-3 and 4)

GLP-1s are serious medications with certain potential toxicities for some patients, including pancreatitis, thyroid cancer, and very rarely, but now officially acknowledged in the case of Wegovy blindness, caused by a condition called non-arteritic anterior ischemic optic neuropathy (NAION)

It is the first and only Semaglutide tablet formulation, providing an effective and convenient alternative to injectable diabetes medications