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Researchers who escalated too quickly bore the brunt of gastrointestinal side effects, while those who followed the standard four-week titration intervals reported significantly better tolerability

Increased appetite/hunger (though this can also be due to the net effect of a boosted metabolism and more muscle mass gains)

There is no need to pinch the skin excessively in most patients, though individuals with minimal subcutaneous fat may benefit from a gentle skin fold to ensure subcutaneous rather than intramuscular injection

Regarding dose reduction , it's important to note that tapering is not routinely required when stopping Ozempic, as there is no evidence-based requirement to do so