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Its structure differs from IGF-1 in that it has 13 additional amino acids at the N-terminus, making it a total of 83 amino acids long

The Xaa7 to Xaa38 corresponds to amino acids substitutions in those positions, the U being a spacer, and B is an acidic terminal group

The biological activity of GIP in adipocytes has been investigated for some time, and although there is a need for better understanding, GIP is implicated in adipocyte carbohydrate and lipid metabolism through regulation of glucose uptake [30], lipolysis [31], and lipoprotein lipase (LPL) activity [32]

Muscles move bones and subject them to shearing forces that strengthen the bone