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The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

In the mouse heart, USP1 expression is markedly higher than the other BMAL1 deubiquitinases, USP2 and USP9X , while in the hypothalamus USP9X was much higher than the others ( USP1 playing a dominant role in cardiac circadian regulation

The GSH:GSSG ratio is one of the most widely used indicators of cellular redox state in laboratory work, which is why glutathione appears in such a large body of analytical and cell-biology literature

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