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However, it is important to note that there are certain groups of people who SHOULD NOT attempt intermittent fasting without close medical supervision: Individuals who are on medication or suffer from chronic diseases such as diabetes mellitus, hypertension, cardiovascular disease (previous heart attack, stroke, peripheral vascular diseases), cancers, etc

Karacabeyli D, Lacaille D, Lu Nea et al (2024) Mortality and major adverse cardiovascular events after glucagon-like peptide-1 receptor agonist initiation in patients with immune-mediated inflammatory diseases and type 2 diabetes: a population-based study

A 2025 narrative review on BPC-157 published in PMC summarizes the musculoskeletal healing evidence across animal models, noting that the peptide demonstrates accelerated recovery of tendons, ligaments, and connective tissue through these overlapping pathways