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If these intermediates build up faster than the Krebs cycle can process them, they become highly toxic, effectively choking the mitochondria and halting the entire energy-producing apparatus
If you're on Topamax but still battle intense urges to binge on your comfort foods during times of stress, grief, or when trying to cope with other difficulties in your life, know that medication alone may not be enough
This covalent phosphorylation initiated by glucagon activates the former and inhibits the latter
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