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In one study, CagriSema achieved an average of about 16% weight loss over 68 weeksthe highest figure reported for this population with any weight-management medication to dateand nearly three-quarters of participants (73.5%) reached a healthy HbA1c target

However, because the injection is fast-acting and bypasses the gut, many patients report a noticeable lift in their energy and mental clarity within 24 to 72 hours

More binding protein means more B12 is held in the blood, pushing serum levels up

Concurrent use of medications that affect b12 absorption Several common medications interfere with b12 absorption through various mechanisms