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Overlapping binding sites of GLP-1 and Fab 3F52 The -helix of the GLP-1R ECD is a critical part of the GLP-1 binding site as shown previously by x-ray crystallography and it is also the primary binding site of Fab 3F52 as shown in this study 31
These changes were paralleled by marked decreases in total, abdominal, leg, and arm fat percentage, along with increases in FFM and total body muscle percentage
- Decrease body fat mass and reduce food intake
About 40% of patients experience some nausea, but it's usually mild and temporary
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